How do you know if an intervention, program, or practice is likely to be effective with a particular subgroup of students? What resources are there to help school, district, and State leaders identify and select evidence-based practices (EBPs)? EBPs play an increasingly prominent role in Federal education policy. In both State Systemic Improvement Plans (SSIPs) and provisions in the Every Student Succeeds Act (ESSA), States are being asked to implement practices and programs that have evidence of effectiveness. This online module is intended to help teachers and leaders at the school, district, and State level identify and select interventions, practices, and programs that have evidence of effectiveness. It guides viewers through several technical assistance websites that review, compile, and summarize the results of existing research on educational practices and clarifies what EBPs are, highlights what to look for when selecting EBPs, and helps guide the selection of EBPs for particular subgroups of students or local contexts.